Protein palmitoylation
in healthy and diseased brain

2nd-3rd September 2024

ABOUT

Warsaw Doctoral School in Natural and Biomedical Sciences
and
the Nencki Institute of Experimental Biology Polish Academy of Sciences 

cordially invite you to an Advanced Lecture Series entitled:

"Protein palmitoylation in healthy and diseased brain"

Protein palmitoylation is a crucial process regulating protein functions in the brain. In recent years, it has been shown that dysfunctions in this process can lead to significant disruptions in neuronal physiology and contribute to the pathophysiological states associated with psychiatric and neurological disorders, including neurodegenerative diseases. Therefore, understanding the mechanisms of protein palmitoylation and its role in the brain pathology is essential for developing new therapeutic strategies. The subject of this research is challenging and methodologically limited. This lecture series aims to present current research problems in brain protein palmitoylation and is open to everyone interested.


It is highly recommended to all Warsaw-4-PhD students! Attending PhD students can earn 1 ECTS.


This event is supported by the Polish National Agency for Academic Exchange, grant no. BPI/STE/2021/1/00034/U/00001 

SPEAKERS

PROGRAMME

2nd September

Chair: Tomasz Wójtowicz 🇵🇱

9:30-10:30 Ladislav

Vyklický 🇨🇿

Laboratory of Cellular Neurophysiology
Institute of Physiology Czech Academy of Sciences 


Palmitoylation controls NMDA receptor function and steroid sensitivity

10:45-11:45 Katarzyna

Kwiatkowska 🇵🇱

Laboratory of Molecular Membrane Biology
Nencki Insititute of Experimental Biology PAS


Protein palmitoylation and its role in innate immune responses

13:00-14:00 Dale

Martin 🇨🇦

NeurdyPhagy Lab

Department of Biology

University of Waterloo


Mapping mislocalization of proteins to identify overlapping therapeutic targets in HD & ALS

14:15- 15:15 Shaun

Sanders 🇨🇦

Department of Molecular and Cellular Biology

University of Guelph


Sticky Neuronal Tactics: S-acylation's Grip on Neuronal Excitability and Brain Cancer

3rd September

Chair: Jakub Włodarczyk 🇵🇱

9:30 - 10:30 Shernaz

Bamji 🇨🇦

Center of Brain Health & Department of
Cellular and Physiological Sciences, Life Sciences Institute
University of British Columbia

S-Acylation in brain development and disease

10:45 - 11:45 Matteo

Spinelli 🇮🇹

Department of Biomedical Sciences
University of Sassari

Aberrant S-Palmitoylation-dependent cognitive decline:
at the crossroads between metabolic and neurodegenerative diseases

13:00 - 14:00 Rebeca M.

Mejías-Estévez 🇪🇸

Department of Physiology, School of Biology
University of Seville

Role of palmitoylation in Parkinson's disease and dopaminergic neurotransmission

14:15 - 15:15 Frédérik

Saudou 🇫🇷

University Grenoble Alpes
Inserm & Grenoble Institute of Neuroscience

Huntington's disease: Linking Huntingtin to Fast Axonal Transport,
Palmitoylation and Neurotrophin Signaling to Neurodegeneration

15:30 - 16:30 Tomasz

Wójtowicz 🇵🇱

Laboratory of Cell Biophysics
Nencki Institute of Experimental Biology PAS

Protein palmitoylation in neuronal plasticity, learning, and memory

VENUE

CN Conference Hall at Nencki Institute of Experimental Biology of the Polish Academy of Sciences 

3 Pasteur Street, 02-093 Warsaw, Poland


ORGANIZERS

CO-ORGANIZERS

Jakub Włodarczyk

Laboratory of Cell Biophysics

Nencki Insititute of Experimental Biology Polish Academy of Sciences

Agata Pytyś

Laboratory of Cell Biophysics

Nencki Insititute of Experimental Biology Polish Academy of Sciences